c-Myc(Phospho Thr58) Polyclonal Antibody

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

The c-Myc(Phospho Thr58) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of c-Myc protein phosphorylated at threonine 58. This antibody is produced using high-quality polyclonal antibodies that have been rigorously tested for specificity and sensitivity. The c-Myc(Phospho Thr58) Polyclonal Antibody is ideal for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry. This antibody is suitable for use in both research and diagnostic applications and has been validated for use in human, mouse, and rat samples. With its high specificity and sensitivity, the c-Myc(Phospho Thr58) Polyclonal Antibody is an essential tool for researchers and clinicians working in the fields of cancer biology, cell signaling, and molecular biology.

The C-MYC(PHOSPHO THR58) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated threonine 58 residue on the C-MYC protein. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target epitope.

The C-MYC protein plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of threonine 58 residue has been implicated in the regulation of C-MYC activity and stability. Therefore, the C-MYC(PHOSPHO THR58) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms underlying C-MYC signaling pathways.

This antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to provide reliable and reproducible results across a wide range of sample types, including cell lysates, tissue sections, and whole-cell extracts.

The C-MYC(PHOSPHO THR58) Polyclonal Antibody is manufactured under stringent quality control standards to ensure batch-to-batch consistency and optimal performance. It is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation steps.

With its exceptional specificity, sensitivity, and versatility, the C-MYC(PHOSPHO THR58) Polyclonal Antibody is an indispensable tool for researchers investigating the role of C-MYC phosphorylation in various biological processes.