BMP3B Polyclonal Antibody

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer.

The BMP3B Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of BMP3B protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human BMP3B protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The BMP3B Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting BMP3B protein in human, mouse, and rat tissues. This antibody has been shown to recognize a single band of the expected molecular weight in Western blot analysis and to produce strong staining in immunohistochemistry experiments. Additionally, this antibody has been shown to exhibit minimal cross-reactivity with other BMP family members, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store this antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles. The BMP3B Polyclonal Antibody is an essential tool for researchers studying BMP3B protein expression and function in various biological systems.