BMP-10 Polyclonal Antibody

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.

The BMP-10 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of BMP-10 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human BMP-10 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and ELISA.

The BMP-10 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting BMP-10 protein in human, mouse, and rat tissues. This antibody has been shown to recognize a single band of the expected molecular weight in Western blot analysis and to produce strong staining in immunohistochemistry experiments. Additionally, this antibody has been shown to exhibit minimal cross-reactivity with other BMP family members, ensuring accurate and reliable results.

This high-quality BMP-10 Polyclonal Antibody is an essential tool for researchers studying the role of BMP-10 in various biological processes, including cardiovascular development, angiogenesis, and bone formation. Its exceptional specificity and sensitivity make it an ideal choice for use in a wide range of research applications. With its reliable performance and consistent results, the BMP-10 Polyclonal Antibody is a valuable addition to any laboratory's research toolkit.