ATP4A Polyclonal Antibody

The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase.

The ATP4A Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ATP4A protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the ATP4A protein. The ATP4A Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ATP4A protein is a subunit of the gastric proton pump, which plays a crucial role in the secretion of gastric acid. Dysregulation of ATP4A expression has been implicated in various gastric disorders, including gastric ulcers and gastric cancer. Therefore, the ATP4A Polyclonal Antibody is an essential tool for researchers studying the role of ATP4A in gastric physiology and pathology.

The ATP4A Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. This antibody is available in various sizes and formats to suit different experimental needs. The ATP4A Polyclonal Antibody is a reliable and high-quality reagent that can provide accurate and reproducible results in various applications.