ATOH8 Polyclonal Antibody

Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation.,Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels.,

The ATOH8 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of ATOH8 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region within the C-terminal domain of the ATOH8 protein.

ATOH8, also known as Math6, is a member of the basic helix-loop-helix (bHLH) transcription factor family. It plays a crucial role in the regulation of embryonic development, particularly in the formation of the central nervous system and skeletal muscle. ATOH8 has been implicated in various physiological and pathological processes, including neurogenesis, myogenesis, and tumorigenesis.

The ATOH8 Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related bHLH transcription factors, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size of 100 µg, allowing for multiple experiments. It is recommended for use in a wide range of applications, including but not limited to, protein expression profiling, cellular localization studies, and functional analysis of ATOH8 in both research and clinical settings.

With its high affinity and specificity, the ATOH8 Polyclonal Antibody offers researchers a valuable tool to unravel the intricate mechanisms underlying ATOH8-mediated processes. Its reliable performance and versatility make it an indispensable asset for scientists studying developmental biology, neurobiology, and cancer research.