BT Lab
SKU:BT-AP14305
ARC Polyclonal Antibody
ARC Polyclonal Antibody
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Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,
The ARC Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of the Activity-Regulated Cytoskeleton-associated protein (ARC) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human ARC protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the ARC protein, making it an ideal tool for various applications in research and diagnostics.
The ARC Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to detect both endogenous and recombinant ARC protein with high sensitivity and specificity. This antibody is supplied as a purified IgG fraction, and has been tested and validated for use in a variety of applications.
In summary, the ARC Polyclonal Antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of the ARC protein in various biological samples. Its high affinity and specificity make it an ideal tool for various applications in research and diagnostics, and its validated performance in multiple immunoassays ensures reliable and reproducible results.
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