ANR28 Polyclonal Antibody

Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.,Contains 27 ANK repeats.,subcellular location:Seems to be excluded from nucleoli.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.,

The ANR28 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of ANR28 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the ANR28 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the ANR28 protein, making it an ideal tool for various applications in research and diagnostics.

The ANR28 Polyclonal Antibody has been extensively validated for its performance in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been shown to detect ANR28 protein in a wide range of species, including human, mouse, rat, and others. The antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography.

The ANR28 Polyclonal Antibody is a valuable tool for researchers studying the role of ANR28 protein in various biological processes, including cell proliferation, differentiation, and apoptosis. It can also be used for the development of diagnostic assays for the detection of ANR28 protein in clinical samples, such as serum, plasma, and tissue specimens.

In summary, the ANR28 Polyclonal Antibody is a highly specific and sensitive immunological reagent that offers excellent performance in various immunoassays. Its high affinity and specificity towards the ANR28 protein make it an ideal tool for research and diagnostic applications.