AMPK alpha2 Polyclonal Antibody

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

The AMPK alpha2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of AMP-activated protein kinase (AMPK) alpha2 subunit in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The AMPK alpha2 Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is an essential tool for researchers studying the regulation of energy metabolism and the role of AMPK in various physiological processes. The AMPK alpha2 Polyclonal Antibody is available in various sizes and formats to meet the specific needs of different research applications. It is a reliable and effective tool for the detection of AMPK alpha2 subunit and is an essential component of any research program focused on the study of AMPK signaling pathways.