AMGO2 Polyclonal Antibody

Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.,Belongs to the immunoglobulin superfamily. AMIGO family.,Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.,subunit:Binds itself as well as AMIGO1 and AMIGO3.,tissue specificity:Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.,

The AMGO2 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The AMGO2 Polyclonal Antibody is ideal for use in immunohistochemistry, western blotting, and other applications where high specificity and sensitivity are required.

This antibody is designed to target the AMGO2 protein, which is a member of the AMIGO family of transmembrane proteins. The AMGO2 protein is involved in the regulation of neuronal development and synaptic plasticity, making it an important target for research in the field of neuroscience.

The AMGO2 Polyclonal Antibody is produced using state-of-the-art techniques and is rigorously tested to ensure its quality and consistency. It is supplied in a convenient format that is easy to use and can be stored for long periods without loss of activity.

Overall, the AMGO2 Polyclonal Antibody is an excellent choice for researchers looking for a reliable and high-quality antibody for their research needs. Its high specificity and sensitivity make it an ideal tool for studying the role of the AMGO2 protein in neuronal development and synaptic plasticity.