Akt1(Phospho Ser129) Polyclonal Antibody

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

The Akt1(Phospho Ser129) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Akt1 protein phosphorylated at Ser129. This antibody is produced using high-quality polyclonal antibodies that have been rigorously tested for specificity and sensitivity. The Akt1(Phospho Ser129) Polyclonal Antibody is ideal for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody is suitable for use in both research and diagnostic applications. The Akt1(Phospho Ser129) Polyclonal Antibody is a reliable and effective tool for the detection of Akt1 protein phosphorylated at Ser129, making it an essential component of any laboratory's research arsenal.

The AKT1(PHOSPHO SER129) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of AKT1 protein phosphorylated at serine 129 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and sensitivity for the target protein.

The AKT1(PHOSPHO SER129) Polyclonal Antibody is suitable for various applications, including western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and performance in multiple experimental settings, making it an ideal choice for researchers in the field.

With its exceptional sensitivity, this antibody allows for the detection of even low levels of AKT1 protein phosphorylated at serine 129 residue, enabling accurate quantification and analysis. Its high specificity ensures minimal cross-reactivity with other proteins, ensuring reliable and precise results.

The AKT1(PHOSPHO SER129) Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. It is provided in a liquid form, allowing for easy handling and storage.

In summary, the AKT1(PHOSPHO SER129) Polyclonal Antibody is a valuable tool for researchers studying AKT1 protein phosphorylation at serine 129 residue. Its high specificity, sensitivity, and ease of use make it an essential component in various experimental techniques, facilitating accurate and reliable results.