ACTG Polyclonal Antibody

Actins are highly conserved proteins that are involved in various types of cell motility| and maintenance of the cytoskeleton. In vertebrates| three main groups of actin isoforms| alpha| beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton| and as mediators of internal cell motility. Actin| gamma 1| encoded by this gene| is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26| a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

The ACTG Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of the ACTG protein. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the ACTG protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The ACTG Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, ELISA, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other proteins. The antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different applications.

In summary, the ACTG Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of the ACTG protein. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians working in a variety of fields, including cancer biology, immunology, and neuroscience.