ACTC Polyclonal Antibody

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms| alpha| beta| and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

The ACTC Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of alpha cardiac actin (ACTC) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ACTC protein. The resulting polyclonal antibody exhibits high affinity and specificity towards ACTC, making it an ideal tool for various applications such as western blotting, immunohistochemistry, and ELISA.

The ACTC Polyclonal Antibody has been extensively validated for its performance and reliability in detecting ACTC in human, mouse, and rat tissues. It has been shown to exhibit minimal cross-reactivity with other actin isoforms, ensuring accurate and specific detection of ACTC. This antibody is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography to ensure high purity and minimal background.

The ACTC Polyclonal Antibody is a valuable tool for researchers studying cardiac development, function, and disease. It can be used to investigate the expression and localization of ACTC in various tissues and cell types, as well as to monitor changes in ACTC expression levels under different physiological and pathological conditions. With its high sensitivity, specificity, and reliability, the ACTC Polyclonal Antibody is an essential reagent for any researcher working in the field of cardiac biology.