ACL6B Polyclonal Antibody

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold| which is an ATP-binding cleft| as a common feature. The ARPs are involved in diverse cellular processes| including vesicular transport| spindle orientation| nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals| which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin| specifically in the brain. Alternative splicing results in multiple transcript variants.

The ACL6B Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of ACL6B protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human ACL6B protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for a wide range of applications in research and diagnostics.

The ACL6B Polyclonal Antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to detect endogenous levels of ACL6B protein in various tissues and cell lines. The antibody is supplied as a purified IgG fraction, and has been tested for its purity, specificity, and activity.

The ACL6B Polyclonal Antibody is a valuable tool for researchers studying the function and regulation of ACL6B protein in various biological processes, including cell proliferation, differentiation, and apoptosis. It can also be used for the development of diagnostic assays for the detection of ACL6B protein in clinical samples, such as serum or tissue biopsies. With its high sensitivity and specificity, the ACL6B Polyclonal Antibody is a reliable and effective reagent for a wide range of applications in life sciences research and clinical diagnostics.