Nibrin(Phospho Ser343) Polyclonal Antibody

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

The Nibrin (Phospho Ser343) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Nibrin protein phosphorylated at Ser343. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Nibrin protein plays a crucial role in DNA damage response and repair pathways, making it an essential target for research in the fields of cancer biology, genomics, and molecular biology. By specifically recognizing the phosphorylated form of Nibrin at Ser343, this polyclonal antibody enables researchers to investigate the intricate signaling mechanisms involved in DNA damage response and gain valuable insights into the underlying molecular processes.

With its high affinity and specificity, the Nibrin (Phospho Ser343) Polyclonal Antibody offers exceptional sensitivity and accuracy in detecting and quantifying phosphorylated Nibrin protein. Its robust performance ensures reliable and reproducible results, allowing researchers to confidently analyze and interpret their experimental data.

This antibody has been extensively validated using a variety of experimental approaches, ensuring its superior quality and performance. It exhibits minimal cross-reactivity with non-phosphorylated Nibrin protein, ensuring precise and specific detection of the phosphorylated form. Furthermore, it demonstrates excellent stability and consistency, providing consistent results across multiple experiments.

The Nibrin (Phospho Ser343) Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, ready for immediate use, eliminating the need for time-consuming reconstitution procedures. Its long shelf life ensures prolonged usability, making it a cost-effective choice for long-term research projects.

In summary, the Nibrin (Phospho Ser343) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of phosphorylated Nibrin protein. Its exceptional performance, sensitivity, and stability make it an ideal choice for researchers studying DNA damage response and repair pathways.