NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines| oxidant-free radicals| ultraviolet irradiation| and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

The NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NFκB-p105/p50 protein phosphorylated at Ser337. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and accuracy in various applications.

The NFκB-p105/p50 protein plays a crucial role in the regulation of immune responses, inflammation, and cell survival. Phosphorylation of Ser337 is known to modulate the activity and function of NFκB-p105/p50, making it an important target for research in various fields, including immunology, oncology, and neurobiology.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays. It exhibits minimal cross-reactivity with non-phosphorylated forms of NFκB-p105/p50, ensuring accurate and reliable results.

With its high affinity and excellent performance, the NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody is an indispensable tool for researchers aiming to investigate the phosphorylation status and functional implications of NFκB-p105/p50 in various biological systems. Its versatility and reliability make it suitable for both basic research and drug development studies.

Order the NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of NFκB signaling pathway and its role in disease progression.

The NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NFκB-p105/p50 protein phosphorylated at Ser337. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and accuracy in various applications.

The NFκB-p105/p50 protein plays a crucial role in the regulation of immune responses, inflammation, and cell survival. Phosphorylation of Ser337 is known to modulate the activity and function of NFκB-p105/p50, making it an important target for research in various fields, including immunology, oncology, and neurobiology.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays. It exhibits minimal cross-reactivity with non-phosphorylated forms of NFκB-p105/p50, ensuring accurate and reliable results.

With its high affinity and excellent performance, the NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody is an indispensable tool for researchers aiming to investigate the phosphorylation status and functional implications of NFκB-p105/p50 in various biological systems. Its versatility and reliability make it suitable for both basic research and drug development studies.

Order the NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of NFκB signaling pathway and its role in disease progression.