XPC Rabbit Polyclonal Antibody

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway| including Xeroderma pigmentosum (XP) A-G and V| Cockayne syndrome (CS) A and B| and trichothiodystrophy (TTD) group A| etc. This component| XPC| plays an important role in the early steps of global genome NER| especially in damage recognition| open complex formation| and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum| a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

The XPC Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection of XPC protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human XPC protein. The resulting polyclonal antibody exhibits high affinity and specificity towards XPC protein, making it an ideal reagent for various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The XPC Rabbit Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its specificity and sensitivity. This antibody recognizes a single band of the expected molecular weight in Western blot analysis, and shows minimal cross-reactivity with other proteins. Additionally, the XPC Rabbit Polyclonal Antibody has been shown to be highly effective in detecting XPC protein in formalin-fixed, paraffin-embedded tissue sections, making it a valuable tool for diagnostic and research purposes.

Overall, the XPC Rabbit Polyclonal Antibody is a reliable and effective reagent for the detection of XPC protein in various biological samples. Its high specificity and sensitivity make it an ideal tool for a wide range of applications, including basic research, drug discovery, and clinical diagnostics.