VCAM1 Rabbit Polyclonal Antibody

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction| and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

The VCAM1 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of VCAM1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human VCAM1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards VCAM1 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The VCAM1 Rabbit Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody has been extensively validated for its specificity and sensitivity in various biological samples, including human, mouse, and rat tissues.

The VCAM1 Rabbit Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different applications. This antibody is suitable for use in both research and diagnostic applications, and it is an essential tool for studying the role of VCAM1 protein in various physiological and pathological processes.