UD11 Rabbit Polyclonal Antibody

This gene encodes a UDP-glucuronosyltransferase| an enzyme of the glucuronidation pathway that transforms small lipophilic molecules| such as steroids| bilirubin| hormones| and drugs| into water-soluble| excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons| resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site| and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin| although it also has moderate activity with simple phenols| flavones| and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

The UD11 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of target proteins in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the target protein, followed by purification and characterization of the resulting polyclonal antibody. The UD11 Rabbit Polyclonal Antibody exhibits excellent specificity and sensitivity, with minimal cross-reactivity to non-target proteins. It is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and ELISA. The UD11 Rabbit Polyclonal Antibody is supplied in a convenient format, with ample quantity and high purity, ensuring consistent and reliable results. It is an essential tool for researchers and scientists in the fields of molecular biology, biochemistry, and biotechnology, enabling them to advance their research and discovery efforts.