UBP18 Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus| and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions| and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues| indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon| suggesting a function of this protein in downregulating interferon responses| independent of its isopeptidase activity towards ISG15.

The UBP18 Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of UBP18 protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure exceptional performance and accuracy in a wide range of applications.

The UBP18 Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers and scientists working in the fields of molecular biology, biochemistry, and cell biology. It has been extensively tested and validated for use in Western blotting, immunohistochemistry, immunofluorescence, and other immunoassay techniques.

This antibody is produced using high-quality rabbit polyclonal antibodies that have been carefully selected and purified to ensure maximum specificity and minimal cross-reactivity. It has been extensively characterized and validated using a variety of techniques, including knockout and overexpression studies, to ensure its reliability and accuracy.

The UBP18 Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient and user-friendly format, allowing for easy and efficient handling.

With its exceptional performance, reliability, and ease of use, the UBP18 Rabbit Polyclonal Antibody is an indispensable tool for researchers and scientists seeking to explore the functions and mechanisms of UBP18 protein in various biological systems.