TNK1(Phospho-Tyr277) Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways| mediating cellular proliferation| survival| and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues| thus may function in signaling pathways utilized broadly during fetal development| and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.The TNK1(Phospho-Tyr277) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of TNK1 protein phosphorylated at tyrosine 277. This antibody has been rigorously validated for use in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The TNK1 protein plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. Phosphorylation of TNK1 at tyrosine 277 has been implicated in the regulation of its enzymatic activity and downstream signaling pathways. Therefore, the ability to accurately measure the levels of TNK1 phosphorylated at this specific site is of utmost importance in understanding its functional significance.

Our TNK1(Phospho-Tyr277) Rabbit Polyclonal Antibody has been developed using state-of-the-art techniques and exhibits exceptional specificity and sensitivity. It has been extensively tested and validated to ensure reliable and reproducible results. This antibody recognizes TNK1 phosphorylated at tyrosine 277 with high affinity, making it an ideal tool for studying the role of TNK1 in various biological processes.

In addition to its high specificity, this antibody also offers versatility in its applications. It can be used for Western blotting to detect and quantify TNK1 phosphorylated at tyrosine 277 in cell lysates or tissue extracts. It can also be used for immunoprecipitation to isolate TNK1 protein complexes for further analysis. Furthermore, it can be utilized for immunofluorescence to visualize the subcellular localization of TNK1 phosphorylated at tyrosine 277.

Overall, the TNK1(Phospho-Tyr277) Rabbit Polyclonal Antibody is a valuable tool for researchers studying TNK1 and its phosphorylation at tyrosine 277. Its exceptional specificity, sensitivity, and versatility make it an essential component of any study aiming to elucidate the functional significance of TNK1 in cellular processes.