Tie2(Phospho-Ser1119) Rabbit Polyclonal Antibody

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains| three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described| but their full-length nature is not known.

The Tie2(Phospho-Ser1119) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated Tie2 protein at serine 1119 residue. This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Tie2 receptor, also known as angiopoietin-1 receptor, plays a crucial role in angiogenesis and vascular development. Phosphorylation of the serine 1119 residue is known to regulate the activation and signaling of Tie2, thereby influencing endothelial cell functions and vascular homeostasis.

Our Tie2(Phospho-Ser1119) Rabbit Polyclonal Antibody has been meticulously developed using high-quality rabbit polyclonal antibodies and advanced purification techniques. It exhibits exceptional specificity towards the phosphorylated serine 1119 residue of Tie2, ensuring accurate and reliable results.

With its superior sensitivity, this antibody allows for the detection of even low levels of phosphorylated Tie2 protein, enabling researchers to study the intricate mechanisms underlying angiogenesis and vascular biology. Its versatility in various applications makes it an indispensable tool for scientists and researchers in the fields of cancer research, cardiovascular biology, and developmental biology.

Order the Tie2(Phospho-Ser1119) Rabbit Polyclonal Antibody today and unlock new insights into the role of Tie2 phosphorylation in angiogenesis and vascular development.