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SKU:BT-AP04881

SQSTM1/p62 Rabbit Polyclonal Antibody

SQSTM1/p62 Rabbit Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

The SQSTM1/p62 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SQSTM1/p62 protein in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity.

SQSTM1/p62, also known as sequestosome-1, is a multifunctional protein involved in various cellular processes, including autophagy, signal transduction, and protein degradation. It acts as a scaffold protein, facilitating the assembly of protein complexes and regulating cellular responses to stress and inflammation.

The SQSTM1/p62 Rabbit Polyclonal Antibody exhibits excellent performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications. It recognizes endogenous levels of SQSTM1/p62 protein in a wide range of species, including human, mouse, and rat.

With its high specificity and sensitivity, this antibody enables accurate and reliable detection of SQSTM1/p62 protein in diverse research areas, such as cancer biology, neurodegenerative diseases, and cellular stress responses. It is an indispensable tool for scientists and researchers aiming to unravel the intricate mechanisms underlying SQSTM1/p62-mediated cellular processes.

The SQSTM1/p62 Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. Each batch of this antibody undergoes rigorous quality control procedures to guarantee consistent and reproducible results.

In summary, the SQSTM1/p62 Rabbit Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of SQSTM1/p62 protein. Its exceptional performance in various applications makes it an invaluable asset for researchers in the field of cellular biology and related disciplines.

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