SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

The SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of SQSTM1/p62 protein phosphorylated at Ser349. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The SQSTM1/p62 protein plays a crucial role in cellular processes such as autophagy, inflammation, and signal transduction. Phosphorylation of Ser349 is known to regulate the function and localization of SQSTM1/p62, making it an important target for research in various fields, including cancer biology, neurodegenerative diseases, and metabolic disorders.

This antibody has been rigorously validated to ensure specificity and sensitivity. It exhibits minimal cross-reactivity with non-phosphorylated SQSTM1/p62 protein and other related proteins, ensuring accurate and reliable results. The high affinity and specificity of this antibody enable precise detection and quantification of phosphorylated SQSTM1/p62 protein in complex biological samples.

The SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready to use for various applications. It is provided in a convenient size, allowing for multiple experiments without compromising performance. The antibody is stored at -20°C, ensuring long-term stability and preserving its activity.

In summary, the SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the role of SQSTM1/p62 protein phosphorylation in various biological processes. Its high specificity, sensitivity, and reliability make it an essential component of any laboratory involved in protein analysis and cellular signaling research.