SMC1(Phospho-Ser360) Rabbit Polyclonal Antibody

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins| SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis| although those complexes at the kinetochore remain. Therefore| the encoded protein is thought to be an important part of functional kinetochores. In addition| this protein interacts with BRCA1 and is phosphorylated by ATM| indicating a potential role for this protein in DNA repair. This gene| which belongs to the SMC gene family| is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Altern

The SMC1(PHOSPHO-SER360) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SMC1 protein phosphorylated at serine 360. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The SMC1(PHOSPHO-SER360) Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise quantification of SMC1 phosphorylation at serine 360. It recognizes the phosphorylated form of SMC1 with high affinity, while exhibiting minimal cross-reactivity with non-phosphorylated SMC1 or other related proteins.

This antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and reproducibility. It has been extensively tested and validated in various cell lines and tissues, guaranteeing reliable and reproducible results. The SMC1(PHOSPHO-SER360) Rabbit Polyclonal Antibody demonstrates excellent performance in both monoclonal and polyclonal antibody-based assays, making it an ideal choice for researchers in the fields of cell biology, molecular biology, and cancer research.

With its superior specificity and sensitivity, the SMC1(PHOSPHO-SER360) Rabbit Polyclonal Antibody offers a valuable tool for investigating the role of SMC1 phosphorylation at serine 360 in cellular processes, such as DNA repair, chromosome segregation, and cell cycle regulation. Its versatility and reliability make it an indispensable asset for researchers aiming to unravel the intricate mechanisms underlying these fundamental biological processes.

Order the SMC1(PHOSPHO-SER360) Rabbit Polyclonal Antibody today and unlock new insights into the dynamic regulation of SMC1 phosphorylation at serine 360, advancing your research endeavors and contributing to the advancement of scientific knowledge.