Smad3(Phospho-Ser423/425) Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the SMAD| a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Introducing the Smad3(Phospho-Ser423/425) Rabbit Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, derived from rabbit polyclonal sources, exhibits exceptional specificity and sensitivity, making it an invaluable tool for the detection and analysis of Smad3 protein phosphorylation at Serine residues 423 and 425.

With its advanced formulation, this antibody offers unparalleled performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its ability to recognize and bind specifically to the phosphorylated form of Smad3 at Ser423/425 ensures accurate and reliable results, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways involving Smad3.

The Smad3(Phospho-Ser423/425) Rabbit Polyclonal Antibody boasts a host of remarkable features that set it apart from its counterparts. Its high affinity and selectivity for the phosphorylated form of Smad3 guarantee minimal cross-reactivity, ensuring precise and specific detection. Furthermore, its robust and consistent performance across a wide range of sample types, including cell lysates and tissue sections, ensures versatility and reliability in experimental settings.

Manufactured under stringent quality control measures, this antibody undergoes rigorous testing to ensure batch-to-batch consistency and reproducibility. Its exceptional stability and long shelf life make it an ideal choice for long-term storage, allowing researchers to conduct experiments at their convenience without compromising the integrity of the antibody.

In summary, the Smad3(Phospho-Ser423/425) Rabbit Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the complexities of Smad3 protein phosphorylation. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset in the field of molecular biology, enabling groundbreaking discoveries and advancements in our understanding of cellular signaling pathways.

The SMAD3(PHOSPHO-SER423/425) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated SMAD3 at serine residues 423 and 425. This antibody is produced using advanced rabbit polyclonal technology, ensuring high affinity and specificity towards the target protein.

SMAD3 is a critical component of the transforming growth factor-beta (TGF-β) signaling pathway, playing a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of SMAD3 at serine residues 423 and 425 is known to regulate its transcriptional activity and downstream signaling events.

The SMAD3(PHOSPHO-SER423/425) Rabbit Polyclonal Antibody offers exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated SMAD3 and other related proteins, ensuring accurate and reliable results.

With its high sensitivity and specificity, this antibody enables researchers to explore the intricate mechanisms of TGF-β signaling and its implications in various physiological and pathological conditions. It is an invaluable tool for studying cellular signaling pathways, cancer research, and drug development.

The SMAD3(PHOSPHO-SER423/425) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, ensuring stability and long shelf life.

In summary, the SMAD3(PHOSPHO-SER423/425) Rabbit Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of phosphorylated SMAD3 at serine residues 423 and 425. Its high specificity, sensitivity, and versatility make it an essential component of any research project focused on TGF-β signaling and related pathways.