Smad2(Phospho-Ser465/467) Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the SMAD| a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta| and thus regulates multiple cellular processes| such as cell proliferation| apoptosis| and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal| this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation

Introducing the Smad2(Phospho-Ser465/467) Rabbit Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, derived from rabbits, exhibits exceptional specificity and sensitivity, making it an invaluable tool for the detection and analysis of Smad2 protein phosphorylation at serine residues 465 and 467.

With its advanced formulation, this antibody offers unparalleled performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. Its ability to recognize and bind specifically to the phosphorylated form of Smad2 at serine residues 465 and 467 ensures accurate and reliable results, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.

The Smad2(Phospho-Ser465/467) Rabbit Polyclonal Antibody has undergone rigorous quality control measures to ensure its superior performance and consistency. Each batch is meticulously tested to guarantee specificity, sensitivity, and minimal cross-reactivity, ensuring the utmost accuracy and reliability in experimental outcomes.

Furthermore, this antibody exhibits exceptional versatility, allowing for compatibility with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins. Its robust and reliable performance, coupled with its broad applicability, makes it an indispensable tool for researchers seeking to unravel the complexities of Smad2 phosphorylation and its implications in various biological processes.

In summary, the Smad2(Phospho-Ser465/467) Rabbit Polyclonal Antibody stands as a pinnacle of scientific excellence, offering researchers an unparalleled tool to investigate and elucidate the intricate mechanisms of Smad2 phosphorylation. With its exceptional specificity, sensitivity, and versatility, this antibody is poised to revolutionize the field of molecular biology and contribute to groundbreaking discoveries in cellular signaling pathways.

The SMAD2(PHOSPHO-SER465/467) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SMAD2 protein phosphorylated at serine residues 465 and 467. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its superior sensitivity and specificity, this antibody enables precise and accurate quantification of SMAD2 phosphorylation levels, facilitating in-depth investigations into the intricate signaling pathways involving SMAD2. Its polyclonal nature ensures robust and consistent results, making it an ideal choice for both basic research and clinical studies.

The SMAD2(PHOSPHO-SER465/467) Rabbit Polyclonal Antibody exhibits excellent performance across a wide range of sample types, including cell lysates, tissue extracts, and whole-cell preparations. Its versatility allows for seamless integration into various experimental setups, providing researchers with the flexibility to explore SMAD2 phosphorylation dynamics in diverse biological contexts.

Furthermore, this antibody has been rigorously tested to ensure minimal cross-reactivity with non-phosphorylated SMAD2 and other related proteins, ensuring the utmost specificity in target detection. Its high affinity and affinity-purified formulation guarantee reliable and reproducible results, enabling confident interpretation of experimental data.

In summary, the SMAD2(PHOSPHO-SER465/467) Rabbit Polyclonal Antibody is a premium research tool that offers exceptional sensitivity, specificity, and versatility. Its reliable performance and robust design make it an indispensable asset for scientists and clinicians alike, facilitating groundbreaking discoveries and advancements in the field of SMAD2 signaling research.