SLP-76(Phospho-Tyr145) Rabbit Polyclonal Antibody

SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation| supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c

The SLP-76(PHOSPHO-TYR145) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SLP-76 protein phosphorylated at tyrosine 145. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its exceptional sensitivity and specificity, this antibody enables precise and accurate detection of SLP-76(PHOSPHO-TYR145) in complex biological samples. It exhibits minimal cross-reactivity with non-phosphorylated SLP-76 and other related proteins, ensuring reliable and specific results.

The SLP-76(PHOSPHO-TYR145) Rabbit Polyclonal Antibody is produced using high-quality rabbit polyclonal antibodies, which have been carefully selected and purified to ensure optimal performance. It has been extensively tested and validated to meet the highest standards of quality and consistency.

This antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, ready for immediate use, eliminating the need for time-consuming reconstitution procedures.

Whether you are conducting basic research, drug discovery, or clinical diagnostics, the SLP-76(PHOSPHO-TYR145) Rabbit Polyclonal Antibody is an indispensable tool for studying the phosphorylation status of SLP-76 protein. Its exceptional performance, reliability, and specificity make it an ideal choice for researchers and scientists in the field.

Order your SLP-76(PHOSPHO-TYR145) Rabbit Polyclonal Antibody today and unlock new insights into the intricate signaling pathways involving SLP-76 protein phosphorylation.