Skp2(Phospho-Ser64) Rabbit Polyclonal Antibody

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box| this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B| also referred to as p27 or KIP1) predominantly in S phase and int

The Skp2(Phospho-Ser64) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Skp2 protein phosphorylated at Ser64. This antibody is produced using high-quality rabbit polyclonal antibodies and is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The Skp2 protein is a key regulator of the cell cycle and is involved in the degradation of several important cell cycle regulators. Phosphorylation of Skp2 at Ser64 has been shown to play a critical role in the regulation of Skp2 activity and stability. The Skp2(Phospho-Ser64) Rabbit Polyclonal Antibody is specifically designed to detect this phosphorylated form of Skp2, making it an essential tool for researchers studying the regulation of the cell cycle and the role of Skp2 in cancer and other diseases.

This antibody has been extensively validated for specificity and sensitivity, ensuring reliable and reproducible results in a wide range of experimental conditions. It is supplied in a convenient format, with sufficient antibody for multiple experiments, and is compatible with a variety of detection methods.

In summary, the Skp2(Phospho-Ser64) Rabbit Polyclonal Antibody is a high-quality, reliable, and specific tool for the detection of phosphorylated Skp2 protein. It is an essential reagent for researchers studying the regulation of the cell cycle and the role of Skp2 in disease.