Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways| the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms| p52Shc and p46Shc| link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms| p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

The SHC(PHOSPHO-TYR317) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of SHC protein phosphorylated at tyrosine 317 residue. This antibody is produced using high-quality rabbit polyclonal serum and is purified using advanced chromatographic techniques to ensure maximum specificity and purity. The SHC(PHOSPHO-TYR317) Rabbit Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It is an essential tool for researchers studying the role of SHC protein in various cellular processes, including cell proliferation, differentiation, and survival. The antibody is supplied in a convenient format and is ready to use, making it an ideal choice for both academic and industrial research applications. With its high sensitivity and specificity, the SHC(PHOSPHO-TYR317) Rabbit Polyclonal Antibody is a reliable and effective tool for the detection and quantification of SHC protein phosphorylated at tyrosine 317 residue.