Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways| the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms| p52Shc and p46Shc| link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms| p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

The SHC(PHOSPHO-SER239/240) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated serine residues at positions 239 and 240 on the SHC protein. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its exceptional sensitivity and specificity, this antibody enables precise and accurate quantification of SHC phosphorylation levels, allowing for in-depth investigations into the signaling pathways involving this critical protein. Its polyclonal nature ensures a broad recognition of the target epitope, enhancing the versatility and applicability of this antibody across different experimental setups.

Manufactured using state-of-the-art techniques and quality-controlled processes, this antibody guarantees consistent and reproducible results, ensuring the reliability and robustness of your research findings. Its high affinity and low background staining contribute to the generation of clear and reliable data, facilitating the interpretation and analysis of experimental results.

The SHC(PHOSPHO-SER239/240) Rabbit Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution, and is compatible with a wide range of commonly used buffers and diluents. Each batch of this antibody undergoes rigorous quality control testing to ensure optimal performance and batch-to-batch consistency.

In summary, the SHC(PHOSPHO-SER239/240) Rabbit Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of phosphorylated serine residues on the SHC protein. Its exceptional sensitivity, specificity, and reproducibility make it an invaluable asset for researchers investigating the intricate signaling pathways involving SHC.