S12A3 Rabbit Polyclonal Antibody

This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome| a disease similar to Bartter's syndrome| that is characterized by hypokalemic alkalosis combined with hypomagnesemia| low urinary calcium| and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

The S12A3 Rabbit Polyclonal Antibody is a highly specific and reliable tool for various immunological applications. This antibody is produced by immunizing rabbits with a synthetic peptide derived from the target protein. It exhibits exceptional affinity and sensitivity, making it an ideal choice for detecting and quantifying the target protein in various biological samples.

The S12A3 Rabbit Polyclonal Antibody offers exceptional versatility, enabling its utilization in a wide range of research areas, including molecular biology, cell biology, and immunohistochemistry. Its robust performance ensures accurate and reproducible results, facilitating precise analysis and interpretation of experimental data.

This antibody is manufactured using state-of-the-art techniques and undergoes rigorous quality control measures to ensure its purity, specificity, and consistency. It is supplied as a liquid formulation, ready for immediate use, eliminating the need for time-consuming reconstitution procedures.

The S12A3 Rabbit Polyclonal Antibody demonstrates minimal cross-reactivity with non-target proteins, ensuring reliable and specific detection. Its high signal-to-noise ratio enhances the sensitivity of assays, enabling the detection of low-abundance target proteins.

With its exceptional performance characteristics and reliable results, the S12A3 Rabbit Polyclonal Antibody is an indispensable tool for researchers in the field of life sciences. It provides a valuable resource for elucidating the functions and mechanisms of the target protein, contributing to advancements in scientific knowledge and potential therapeutic applications.