RhoA(Phospho Ser188) Rabbit Polyclonal Antibody

This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape| attachment| and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

The RHOA(PHOSPHO SER188) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of RHOA protein phosphorylated at serine 188. This antibody has been meticulously developed using advanced immunization techniques in rabbits, resulting in a high affinity and specificity towards the phosphorylated form of RHOA at serine 188.

The RHOA protein plays a crucial role in various cellular processes, including cell migration, cytoskeletal organization, and cell adhesion. Phosphorylation of RHOA at serine 188 has been implicated in the regulation of its activity and downstream signaling pathways. Therefore, the ability to accurately detect and quantify this phosphorylated form of RHOA is of utmost importance in understanding its functional implications.

This polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated RHOA and other related proteins, ensuring reliable and accurate results.

The RHOA(PHOSPHO SER188) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use in various applications. It is provided in a convenient size and concentration, allowing for flexibility in experimental design and optimization. The antibody has been purified using state-of-the-art techniques to ensure high purity and minimal background noise.

In summary, the RHOA(PHOSPHO SER188) Rabbit Polyclonal Antibody is a valuable tool for researchers studying RHOA signaling pathways and its phosphorylation events. Its high specificity, sensitivity, and reliability make it an ideal choice for a wide range of applications, including protein expression analysis, cellular localization studies, and functional characterization of RHOA in various biological systems.