Rad18(Phospho-Ser403) Rabbit Polyclonal Antibody

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6| which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart| this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif.  Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

The RAD18(PHOSPHO-SER403) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of RAD18 protein phosphorylated at serine 403. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The RAD18 protein plays a crucial role in DNA damage response and repair pathways, making it an essential target for research in the field of molecular biology. By specifically recognizing the phosphorylated form of RAD18 at serine 403, this antibody enables precise investigation of the protein's function and regulation.

Manufactured using state-of-the-art techniques, this rabbit polyclonal antibody exhibits high affinity and sensitivity towards its target. It has been rigorously tested to ensure minimal cross-reactivity with non-phosphorylated RAD18 and other related proteins, ensuring accurate and reliable results.

The RAD18(PHOSPHO-SER403) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into your experimental workflow. Its exceptional specificity and sensitivity make it an indispensable tool for researchers studying DNA damage response pathways, cell cycle regulation, and related fields.

Choose the RAD18(PHOSPHO-SER403) Rabbit Polyclonal Antibody for its exceptional performance, reliability, and specificity, and unlock new insights into the intricate mechanisms of DNA damage repair.