PSB11 Rabbit Polyclonal Antibody

Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes| complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7| beta-1 to -7| beta-1 to -7| and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307)| beta-2 (PSMB7; MIM 604030)| and beta-5 (PSMB5; MIM 600306). Three additional subunits| beta-1i (PSMB9; MIM 177045)| beta-2i (PSMB10; MIM 176847)| and beta-5i (PSMB8; MIM 177046)| are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11| or beta-5t| is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al.| 2007

The PSB11 Rabbit Polyclonal Antibody is a highly specific and reliable tool for various immunological applications. This antibody is produced by immunizing rabbits with a synthetic peptide derived from the PSB11 protein sequence. It exhibits exceptional affinity and sensitivity towards PSB11, making it an ideal choice for detecting and quantifying PSB11 in biological samples.

The PSB11 Rabbit Polyclonal Antibody is designed to provide accurate and reproducible results in a wide range of experimental settings. It has been extensively validated for use in Western blotting, immunohistochemistry, immunofluorescence, and enzyme-linked immunosorbent assays (ELISA). Its versatility allows for the detection of PSB11 in various sample types, including cell lysates, tissue extracts, and biological fluids.

This antibody offers several advantages over other commercially available antibodies. Its polyclonal nature ensures a high degree of specificity, as it recognizes multiple epitopes on the PSB11 protein. Additionally, the PSB11 Rabbit Polyclonal Antibody exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

The PSB11 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a 1 mg/mL concentration, ensuring sufficient antibody for multiple experiments. The antibody is also available in different sizes to accommodate various experimental needs.

In summary, the PSB11 Rabbit Polyclonal Antibody is a superior tool for the detection and quantification of PSB11 in various immunological applications. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset for researchers in the field.