PDLI2 Rabbit Polyclonal Antibody

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein| and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The PDLI2 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of programmed death ligand 2 (PDLI2) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PDLI2 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PDLI2 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The PDLI2 Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography. This ensures high purity and minimal cross-reactivity with other proteins. The antibody is also validated for use in various species, including human, mouse, and rat. With its high sensitivity and specificity, the PDLI2 Rabbit Polyclonal Antibody is an essential tool for researchers studying the role of PDLI2 in various biological processes and diseases.