PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

The PDHK1(PHOSPHO TYR243) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of PDHK1 protein phosphorylated at tyrosine 243. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The PDHK1(PHOSPHO TYR243) Rabbit Polyclonal Antibody is produced from high-quality rabbit serum, ensuring consistent and reproducible results. It has been extensively validated through rigorous testing to guarantee its performance and reliability. This antibody specifically recognizes the phosphorylated form of PDHK1 at tyrosine 243, making it an invaluable tool for studying the regulation and function of PDHK1 in cellular processes.

With its superior sensitivity, this antibody allows for the detection of even low levels of phosphorylated PDHK1, enabling researchers to accurately quantify and analyze its expression in various biological samples. Its exceptional specificity ensures minimal cross-reactivity with non-phosphorylated PDHK1 or other proteins, providing reliable and accurate results.

The PDHK1(PHOSPHO TYR243) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid form, eliminating the need for reconstitution, and is compatible with a wide range of experimental techniques and applications.

In summary, the PDHK1(PHOSPHO TYR243) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated PDHK1 at tyrosine 243. Its exceptional sensitivity, specificity, and ease of use make it an essential reagent for researchers studying the role of PDHK1 in various biological processes.