PCDB7 Rabbit Polyclonal Antibody

This gene is a member of the protocadherin beta gene cluster| one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes| each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters| the transcripts from these genes are made up of only one large exon| not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site.

The PCDB7 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the target protein. The PCDB7 Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various assays, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is suitable for detecting endogenous levels of the target protein in various tissues and cell types. The PCDB7 Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography. This antibody is provided in a convenient format, with a concentration of 1 mg/mL, and is suitable for use in both basic and clinical research applications. The PCDB7 Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can be used to advance scientific knowledge in various fields, including cancer research, immunology, and neuroscience.