p53 Rabbit Polyclonal Antibody

This gene encodes a tumor suppressor protein containing transcriptional activation| DNA binding| and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes| thereby inducing cell cycle arrest| apoptosis| senescence| DNA repair| or changes in metabolism. Mutations in this gene are associated with a variety of human cancers| including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546| 20937277).

The P53 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of the P53 protein. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the P53 protein.

The P53 Rabbit Polyclonal Antibody exhibits exceptional affinity and selectivity towards the P53 protein, enabling accurate and reliable detection in various experimental applications. It has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays.

With its superior sensitivity, this antibody allows for the detection of even low levels of P53 protein expression, making it an ideal choice for researchers working with limited sample quantities. Its robust performance ensures consistent and reproducible results, facilitating precise quantification and analysis of P53 protein levels.

The P53 Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation procedures. Its long shelf life and stability ensure reliable performance over an extended period, reducing experimental variability and enhancing experimental efficiency.

In summary, the P53 Rabbit Polyclonal Antibody is a valuable tool for researchers studying the P53 protein. Its exceptional sensitivity, specificity, and ease of use make it an indispensable asset in various immunological applications, enabling accurate and reliable detection and analysis of P53 protein expression.