p21 (Acetyl Lys161/K163) Rabbit Polyclonal Antibody

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.|induction:By p53| mezerein (antileukemic compound) and interferon beta.|PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.|Belongs to the CDI family.|tissue specificity:Expressed in all adult human tissues| with 5-fold lower levels observed in the brain.|

Introducing the P21 (Acetyl Lys161/K163) Rabbit Polyclonal Antibody, a highly specific and sensitive tool for the detection and quantification of P21 protein in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies that have been raised against the acetylated lysine residues 161 and 163 of the P21 protein.

The P21 protein is a key regulator of cell cycle progression and is involved in the control of cell proliferation, differentiation, and apoptosis. The acetylation of lysine residues 161 and 163 has been shown to play a critical role in the regulation of P21 activity. Therefore, the P21 (Acetyl Lys161/K163) Rabbit Polyclonal Antibody is an essential tool for researchers studying the function and regulation of P21 protein in various biological processes.

This antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been shown to detect endogenous levels of P21 protein in various cell lines and tissues, making it an ideal tool for both basic and clinical research.

In summary, the P21 (Acetyl Lys161/K163) Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can be used to study the function and regulation of P21 protein in various biological processes. Its specificity and sensitivity make it an essential tool for researchers in the fields of cell biology, cancer research, and drug discovery.