p21 (Acetyl Lys154) Rabbit Polyclonal Antibody

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.|induction:By p53| mezerein (antileukemic compound) and interferon beta.|PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.|Belongs to the CDI family.|tissue specificity:Expressed in all adult human tissues| with 5-fold lower levels observed in the brain.|

The P21 (Acetyl Lys154) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of P21 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional affinity and sensitivity towards the target protein.

The P21 protein, also known as cyclin-dependent kinase inhibitor 1, plays a crucial role in cell cycle regulation and tumor suppression. The acetylation of Lys154 residue in P21 has been shown to modulate its stability and function, making it an important post-translational modification to study.

This rabbit polyclonal antibody has been rigorously validated for its specificity and selectivity, ensuring minimal cross-reactivity with other proteins. It has been extensively tested in various experimental conditions, including Western blotting, immunohistochemistry, and immunofluorescence, consistently delivering accurate and reproducible results.

The P21 (Acetyl Lys154) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into your research workflow. It is provided in a liquid formulation, ensuring optimal stability and long shelf life. The antibody is also available in different sizes to accommodate various experimental needs.

With its exceptional performance and reliability, the P21 (Acetyl Lys154) Rabbit Polyclonal Antibody is an indispensable tool for researchers studying cell cycle regulation, tumor biology, and related fields. Trust in its superior quality to advance your scientific investigations and uncover new insights into the intricate mechanisms governing cellular processes.