OGT(Phospho Thr454) Rabbit Polyclonal Antibody

This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues| the two processes may compete for sites| or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

The OGT(PHOSPHO THR454) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of O-GlcNAc transferase (OGT) phosphorylated at threonine 454. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its exceptional sensitivity and specificity, this antibody enables precise and accurate detection of OGT phosphorylated at threonine 454, facilitating in-depth investigations into the functional role of this post-translational modification. Its polyclonal nature ensures a broad recognition of the target protein, enhancing the versatility of this antibody for use in diverse experimental settings.

The OGT(PHOSPHO THR454) Rabbit Polyclonal Antibody exhibits outstanding performance in Western blotting, providing clear and sharp bands with minimal background noise. Its high affinity and selectivity enable reliable detection of even low-abundance phosphorylated OGT, ensuring accurate quantification and analysis of protein expression levels.

Furthermore, this antibody demonstrates excellent performance in immunoprecipitation assays, allowing for the efficient isolation and enrichment of OGT phosphorylated at threonine 454. This feature facilitates downstream applications such as mass spectrometry and proteomic analysis, enabling comprehensive characterization of the interactome and downstream signaling pathways associated with this phosphorylation event.

In addition, the OGT(PHOSPHO THR454) Rabbit Polyclonal Antibody is compatible with immunofluorescence techniques, enabling visualization and localization of phosphorylated OGT within cells and tissues. Its exceptional specificity ensures precise and reliable staining, enabling accurate subcellular localization studies and co-localization analysis with other cellular markers.

Manufactured to the highest quality standards, this antibody undergoes rigorous quality control procedures to ensure batch-to-batch consistency and reproducibility. It is supplied in a convenient and ready-to-use format, allowing for immediate application in various experimental protocols.

In summary, the OGT(PHOSPHO THR454) Rabbit Polyclonal Antibody is a valuable tool for researchers studying OGT phosphorylation at threonine 454. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset for elucidating the functional significance of this post-translational modification in various biological processes.