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SKU:BT-AP03881

NUDT5 Rabbit Polyclonal Antibody

NUDT5 Rabbit Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates| including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues| resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

The NUDT5 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of NUDT5 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human NUDT5 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The NUDT5 Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 18 kDa in Western blot analysis of NUDT5 protein in various cell lines and tissues. The antibody also shows strong staining of NUDT5 protein in formalin-fixed, paraffin-embedded human tissues in immunohistochemistry.

This antibody is an essential tool for researchers studying the function and regulation of NUDT5 protein in various biological processes, including DNA repair, RNA processing, and metabolism. It is also useful for diagnostic applications, such as the detection of NUDT5 protein in cancer tissues.

In summary, the NUDT5 Rabbit Polyclonal Antibody is a reliable and high-quality antibody that provides accurate and reproducible results in various applications. Its specificity and sensitivity make it an ideal tool for researchers and clinicians working in the field of molecular biology and cancer research.

The NUDT5 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NUDT5 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and sensitivity towards NUDT5.

With its exceptional performance, this antibody offers researchers a valuable resource for investigating the role of NUDT5 in cellular processes and disease mechanisms. Its polyclonal nature ensures a broad recognition of different epitopes, enhancing the versatility of this antibody for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The NUDT5 Rabbit Polyclonal Antibody exhibits minimal cross-reactivity with other proteins, ensuring accurate and specific results. Its robust and reproducible performance guarantees consistent and reliable data, enabling researchers to confidently draw conclusions from their experiments.

Manufactured under stringent quality control measures, this antibody undergoes rigorous testing to ensure its purity, specificity, and functionality. It is supplied in a convenient and ready-to-use format, allowing for immediate application in the laboratory.

Choose the NUDT5 Rabbit Polyclonal Antibody for its exceptional quality, reliability, and specificity, and unlock new insights into the intricate workings of NUDT5 in biological systems.

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