NPC1 Rabbit Polyclonal Antibody

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus| 13 transmembrane domains| and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease| a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

The NPC1 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the NPC1 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional sensitivity and specificity.

The NPC1 Rabbit Polyclonal Antibody exhibits a strong affinity towards the NPC1 protein, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior performance guarantees accurate and reproducible results, enabling researchers to confidently investigate the expression and localization of NPC1 in different tissues and cell types.

This antibody is produced using high-quality rabbit polyclonal antibodies, which have been extensively validated to ensure batch-to-batch consistency and reliability. Its exceptional purity and low background staining contribute to the generation of clear and reliable data, facilitating precise and meaningful scientific conclusions.

The NPC1 Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for immediate application in various experimental settings. Its long shelf life and stability ensure consistent performance over time, making it a valuable asset for long-term research projects.

In summary, the NPC1 Rabbit Polyclonal Antibody is a highly specific and reliable tool that offers exceptional sensitivity and specificity for the detection and analysis of the NPC1 protein. Its superior performance, batch-to-batch consistency, and convenient format make it an indispensable resource for researchers in the field of molecular biology and related disciplines.

The NPC1 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NPC1 protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity.

The NPC1 Rabbit Polyclonal Antibody exhibits excellent performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes the NPC1 protein with high affinity, enabling accurate and precise quantification of its expression levels.

With its superior sensitivity, this antibody allows for the detection of even low levels of NPC1 protein, making it an ideal choice for researchers working with limited sample quantities. Its robust and reliable performance ensures consistent and reproducible results, facilitating the advancement of scientific research.

The NPC1 Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparations. It is provided in a liquid formulation, allowing for easy handling and minimizing the risk of experimental errors.

In summary, the NPC1 Rabbit Polyclonal Antibody is a valuable tool for researchers studying NPC1 protein expression. Its exceptional sensitivity, specificity, and reliability make it an indispensable asset in various applications, enabling accurate and efficient analysis of NPC1 protein levels in biological samples.