NOTCH3 (Cleaved-Val1662) Rabbit Polyclonal Antibody

NOTCH3 (Cleaved-Val1662) Rabbit Polyclonal Antibody

The NOTCH3 (Cleaved-Val1662) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection of NOTCH3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the cleaved Val1662 region of human NOTCH3 protein. The antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity by various immunoassays, including Western blotting, immunohistochemistry, and ELISA.

The NOTCH3 protein is a transmembrane receptor that plays a crucial role in cell differentiation, proliferation, and apoptosis. The cleavage of NOTCH3 at Val1662 site is a critical step in the activation of the NOTCH signaling pathway, which is involved in various physiological and pathological processes, including cancer, cardiovascular diseases, and neurodegenerative disorders. Therefore, the detection of cleaved NOTCH3 protein is of great importance in understanding the molecular mechanisms underlying these diseases.

The NOTCH3 (Cleaved-Val1662) Rabbit Polyclonal Antibody is a valuable tool for researchers working in the fields of cancer biology, cardiovascular research, and neuroscience. It can be used for the detection of cleaved NOTCH3 protein in various sample types, including cell lysates, tissue homogenates, and biological fluids. The antibody is supplied as a liquid formulation in PBS buffer containing 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term use.

In summary, the NOTCH3 (Cleaved-Val1662) Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can facilitate the detection and analysis of cleaved NOTCH3 protein in various biological samples. Its specificity, sensitivity, and versatility make it an ideal choice for researchers seeking to elucidate the role of NOTCH3 signaling in health and disease.

The NOTCH3 (CLEAVED-VAL1662) Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NOTCH3 protein in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity.

The NOTCH3 protein plays a crucial role in various cellular processes, including cell differentiation, proliferation, and apoptosis. It is involved in the regulation of embryonic development and tissue homeostasis. Dysregulation of NOTCH3 has been implicated in several diseases, including cancer and cardiovascular disorders.

This antibody specifically targets the cleaved form of NOTCH3 at Val1662, a critical site involved in the activation of downstream signaling pathways. By detecting this cleaved form, researchers can gain valuable insights into the activation and function of NOTCH3 in different cellular contexts.

The NOTCH3 (CLEAVED-VAL1662) Rabbit Polyclonal Antibody exhibits excellent performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring accurate and reproducible results.

With its high affinity and selectivity, this antibody offers researchers a powerful tool to investigate the role of NOTCH3 in normal physiological processes and disease pathogenesis. Its reliable performance and consistent results make it an indispensable asset for any laboratory studying NOTCH3 biology.

Order the NOTCH3 (CLEAVED-VAL1662) Rabbit Polyclonal Antibody today and unlock the potential of your research by unraveling the intricate mechanisms of NOTCH3 signaling.