NOD1 Rabbit Polyclonal Antibody

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling| LRRs participate in protein-protein interactions| and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described| but the full-length nature of these variants has not been determined.

The NOD1 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of NOD1 protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity in immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting applications.

The NOD1 Rabbit Polyclonal Antibody exhibits excellent performance in detecting endogenous levels of NOD1 protein in human, mouse, and rat tissues. It recognizes an epitope within the N-terminal region of NOD1, making it an ideal choice for investigating the cellular localization and functional role of NOD1 in diverse research areas, including immunology, inflammation, and host defense mechanisms.

With its superior sensitivity and low background, this antibody enables accurate and reproducible results, facilitating precise quantification and analysis of NOD1 protein expression levels. Its robust performance and versatility make it an indispensable tool for researchers aiming to unravel the intricate molecular mechanisms underlying NOD1-mediated signaling pathways.

The NOD1 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a 100 µg size, ensuring ample quantity for multiple experiments. This antibody has been rigorously tested for quality and performance, guaranteeing consistent and reliable results.

In summary, the NOD1 Rabbit Polyclonal Antibody is a highly specific and sensitive tool that offers exceptional performance in detecting and analyzing NOD1 protein expression. Its versatility and reliability make it an invaluable asset for researchers in various fields, enabling in-depth investigations into the functional significance of NOD1 in biological processes.