NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates| thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel| ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of NEDD4L protein phosphorylated at Ser448. This antibody is produced using high-quality rabbit polyclonal antibodies and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The antibody has been rigorously tested to ensure its specificity and sensitivity, and it is guaranteed to provide reliable and reproducible results. With its exceptional performance and versatility, the NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody is an essential tool for researchers studying the role of NEDD4L in various biological processes.

The NEDD4L Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of NEDD4L protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human NEDD4L protein. The resulting polyclonal antibody exhibits high affinity and specificity towards NEDD4L protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The NEDD4L Rabbit Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its specificity and sensitivity. This antibody recognizes a single band of approximately 110 kDa in Western blot analysis of various cell lysates, and shows minimal cross-reactivity with other related proteins. Additionally, this antibody has been shown to be highly effective in detecting endogenous NEDD4L protein in various tissues, including brain, heart, liver, and kidney.

The NEDD4L Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different applications. This antibody is provided in a buffer containing 0.02% sodium azide as a preservative, and should be stored at -20°C upon receipt. With its high specificity and sensitivity, the NEDD4L Rabbit Polyclonal Antibody is an essential tool for researchers studying the role of NEDD4L protein in various biological processes.

Introducing the NEDD4L(PHOSPHO-SER448) Rabbit Polyclonal Antibody, a highly specific and sensitive tool for the detection of NEDD4L protein phosphorylated at serine 448. This antibody has been rigorously tested and validated for use in a variety of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The NEDD4L(PHOSPHO-SER448) Rabbit Polyclonal Antibody is produced using state-of-the-art techniques and high-quality materials to ensure optimal performance and reproducibility. It has been designed to recognize a specific epitope on the NEDD4L protein that is phosphorylated at serine 448, making it an ideal tool for studying the regulation of NEDD4L activity and its role in various cellular processes.

This antibody is supplied in a convenient format, with ample quantities for multiple experiments. It has been extensively characterized and validated for specificity, sensitivity, and reproducibility, ensuring reliable and consistent results.

In summary, the NEDD4L(PHOSPHO-SER448) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the NEDD4L protein and its phosphorylation at serine 448. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its rigorous validation ensures reliable and consistent results.