NAGS Rabbit Polyclonal Antibody

The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI)| the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and| thereby| CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

The NAGS Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of N-acetylglutamate synthase (NAGS) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the NAGS protein. The resulting polyclonal antibody exhibits high affinity and specificity towards NAGS, making it an ideal tool for various applications in research and diagnostics.

The NAGS Rabbit Polyclonal Antibody is suitable for use in various immunoassays, including Western blotting, ELISA, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other related proteins. This antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different applications.

In summary, the NAGS Rabbit Polyclonal Antibody is a reliable and high-quality reagent that offers exceptional sensitivity and specificity for the detection and quantification of NAGS in various biological samples. Its versatility and ease of use make it an essential tool for researchers and clinicians working in the fields of biochemistry, molecular biology, and medicine.