MYPT1(Phospho-Ser507) Rabbit Polyclonal Antibody

Myosin phosphatase target subunit 1| which is also called the myosin-binding subunit of myosin phosphatase| is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation| which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound| active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase| which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase)| which is activated by GTP. RhoA| phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosph

The MYPT1(Phospho-Ser507) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of MYPT1 protein phosphorylated at Ser507. This antibody is produced using high-quality rabbit polyclonal antibodies and is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The MYPT1(Phospho-Ser507) Rabbit Polyclonal Antibody has been rigorously tested to ensure its specificity and sensitivity. It has been validated for use in a range of species, including human, mouse, and rat, and has been shown to detect endogenous levels of MYPT1 protein phosphorylated at Ser507.

This antibody is supplied in a convenient format, with a concentration of 1 mg/mL, and is provided in a 100 µL vial. It is recommended for use at a dilution of 1:1000 for Western blotting and 1:200 for immunohistochemistry.

Overall, the MYPT1(Phospho-Ser507) Rabbit Polyclonal Antibody is a reliable and effective tool for the detection of MYPT1 protein phosphorylated at Ser507, making it an essential reagent for researchers studying the regulation of smooth muscle contraction and other related processes.