MTCH2 Rabbit Polyclonal Antibody

This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus| which is highly expressed in white adipose tissue and adipocytes| and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target| and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

The MTCH2 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of MTCH2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human MTCH2 protein. The resulting antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The MTCH2 Rabbit Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to detect endogenous levels of MTCH2 protein in human, mouse, and rat tissues. This antibody is also suitable for use in studies investigating the role of MTCH2 in various cellular processes, including apoptosis, mitochondrial function, and metabolism.

The MTCH2 Rabbit Polyclonal Antibody is provided as a liquid solution in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research projects. This antibody is a valuable tool for researchers studying the function and regulation of MTCH2 protein in various biological systems.