MMP13 (Cleaved-Tyr104) Rabbit Polyclonal Antibody

cofactor:Binds 2 zinc ions per subunit.|cofactor:Binds 4 calcium ions per subunit.|disease:Defects in MMP13 are the cause of spondyloepimetaphyseal dysplasia type 2 (SEMD

The MMP13 (Cleaved-Tyr104) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cleaved Tyr104 of the MMP13 protein. This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

MMP13, also known as collagenase 3, is a member of the matrix metalloproteinase (MMP) family. It plays a crucial role in extracellular matrix remodeling and tissue homeostasis. The cleavage of Tyr104 in MMP13 is an important post-translational modification that regulates its enzymatic activity and substrate specificity.

This rabbit polyclonal antibody has been generated using a highly purified synthetic peptide corresponding to the cleaved Tyr104 region of MMP13. It exhibits exceptional specificity towards the cleaved form of MMP13, ensuring accurate and reliable results. The antibody has been validated using both recombinant MMP13 protein and cell lysates, demonstrating its suitability for various sample types.

With its high sensitivity, this antibody allows for the detection of even low levels of cleaved Tyr104 MMP13, enabling researchers to study its role in various biological processes and diseases. Its versatility in different applications makes it an invaluable tool for researchers in the fields of cancer research, tissue engineering, and regenerative medicine.

The MMP13 (Cleaved-Tyr104) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and reproducibility. It is provided in a liquid form, allowing for easy handling and storage. Each batch of antibody undergoes rigorous quality control testing to ensure consistent performance and reliability.

In summary, the MMP13 (Cleaved-Tyr104) Rabbit Polyclonal Antibody is a highly specific and sensitive tool that enables the detection and quantification of cleaved Tyr104 of the MMP13 protein. Its exceptional performance in various applications makes it an essential reagent for researchers studying MMP13 and its role in various biological processes and diseases.2)